A noninvasive method to determine intracranial pressure fluctuations from MR measurements of cerebrospinal fluid flow in the spinal canal
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The periodic fluctuation of the intracranial pressure induced by the cardiac cycle is an important physiological signal that plays a role in many pathologies of the central nervous system. Currently, it can only be measured invasively with a pressure sensor inserted through a burr hole in the skull. Here, we present a noninvasive method to determine the intracranial pressure fluctuations from magnetic resonance measurements of cerebrospinal fluid flow in the spinal canal.